Inhibitor

SGC-CBP30 | 27650-1 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: CREBBP (CBP) and EP300 are general transcriptional...

1,10-Phenanthroline, Monohydrate | 27713 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of JAMM-family isopeptidases...

Cilomilast | 27742-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Cilomilast, also known as...

Z-DQMD-FMK | 27666-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Z-DQMD-FMK is a potent cell-permeable inhibitor of caspase-3...

Tubastatin A | 27663-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: N/A Product Type: Inhibitor ...

I-BET151 (GSK1210151A) | 27629-2 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the...

Boc-D-FMK | 27611-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Boc-D-FMK is a cell-permeable broad-spectrum caspase inhibitor that...

AZD2461 | 27606-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: Unlike treatment with AZD 2281 (Olaparib, Axon 1464), AZD 2461...

Z-DEVD-FMK | 27314 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: Caspase-3 Inhibitor Product Type: Inhibitor ...

Tranylcypromine (2-PCPA) | 27305 | Gentaur US, UK & Europe Disrtribition Category: Demethylase/Inhibitors / Activators Application: N/A Background: N/A Description: Tranylcypromine...

EPZ015666 | 79043-1 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: N/A Description: EPZ015666 is a potent,...

AG-14361 | 27602-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: A 17-hour exposure of A549 cells to 0.4 µM AG14361 does not...

EPZ004777 | 27622 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ004777 selectively inhibits cellular H3K79...

Vinpocetine | 27778-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Vinpocetine, also known as...

DBeQ | 27703-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for the study of the ubiquitin-dependent and endoplasmic...

b-AP15 (NSC-687852) | 27701-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Suitable for validation studies of the deubiquitinating...

Aminophylline | 27731 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Aminophylline is a bronchodilator that is used...

MC1568 | 27761-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: MC1568, a derivative of (Aryloxopropenyl)pyrrolyl...

Ezetimibe | 27749-3 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: Ezetimibe has been reported to be a cholesterol...

Tenovin-6 | 27661-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Tenovin-6 is the water soluble...

Rucaparib (AG-014699,PF-01367338) | 27647-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: Rucaparib, also named as AG-014699 or...

Romidepsin (FK228, depsipeptide) | 27646-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Romidepsin is a bicyclic...

EPZ-6438 | 27626-1 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ-6438 competitively binds to the...

AR-42 (OSU-HDAC42) | 27603-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: AR-42 induces histone H3 acetylation,...

Bromosporine | 27612 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the targeting...

UNC1215 | 27406 | Gentaur US, UK & Europe Disrtribition Category: Methyl-lysine Reader/Inhibitors / Activators Application: N/A Background: N/A Description: UNC 1215 is a methyl-lysine...

VX-765 | 27779-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VX-765 is an orally-absorbed pro-drug of VRT-043198, a potent and...

Pracinostat (SB939) | 27771-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Pracinostat (SB939) is an orally...

UNC669 | 27664-2 | Gentaur US, UK & Europe Disrtribition Category: Methyl-lysine Reader/Inhibitors / Activators Application: N/A Background: N/A Description: UNC669 is a potent and...

I-BET151 (GSK1210151A) | 27629-1 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the...

(-)-JQ1 | 27334 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: (-)-JQ1 is the inactive stereoisomer of the potent,...

Cilostazol | 27743-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Cilostazol (OPC-13013, Pletal) is a...

NSC-632839 | 27709-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for non-specific inhibition of ubiquitin-like isopeptidases for...

Tadalafil | 27657-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Tadalafil is a small-molecule inhibitor of...

Roflumilast | 27645-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: The enzyme PDE-4 is found mainly in...

JW 55 | 27633-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: Inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2)...

Wnt-C59 | 27780-3 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: Wnt-C59 prevents palmitoylation of Wnt proteins by Porcupine (a...

PCI-24781 (CRA-024781) | 27769-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: PCI-24781 is a pan-HDAC inhibitor that...

NVP-BEP800 | 27766-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: NVP-BEP800 binds to the N-terminal ATP-binding pocket of...

NSC697923 | 27765-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: N/A Background: NSC697923 selectively inhibits PMA-induced NF-?B...

WP1130 | 27722-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Suitable for cell-based studies of USP function. Background: N/A ...

LDN-57444 | 27706-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for the inhibition of Ubiquitin C-terminal Hydrolase (UCH-L1) in...

Rocilinostat (ACY-1215) | 27644-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Rocilinostat, also...

VER 155008 | 27777-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: VER 155008 is a potent inhibitor of heat shock...

ML161 | 27764-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: ML-161 is thought to act allosterically. ML-161 inhibits...

ICG 001 | 27752-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: ICG001 selectively inhibits colon carcinoma cell lines (SW480...

RGFP966 | 27643-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: RGFP966 is a slow-on/slow-off, competitive tight-binding...

GSK J4 HCl | 27627-1 | Gentaur US, UK & Europe Disrtribition Category: Demethylase/Inhibitors / Activators Application: N/A Background: GSK J4 is a potent cell-permeable inhibitor of the...

AZD2461 | 27606-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: Unlike treatment with AZD 2281 (Olaparib, Axon 1464), AZD 2461...

A-966492 | 27601-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: A-966492 is one of the most potent PARP inhibitors. A-966492...

ND-630 | 27071-1 | Gentaur US, UK & Europe Disrtribition Category: Metabolic Enzymes/Inhibitors Application: N/A Background: N/A Description: ND-630 (NDI 010976) is a highly specific,...

Tubacin | 27662 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Tubacin is a highly potent and...

Sodium Phenylbutyrate | 27654 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Sodium Phenylbutyrate is...

IWP-L6 | 27755-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: WP-L6 was developed as a sub-nanomolar inhibitor of Porcupine,...

Ezetimibe | 27749-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: Ezetimibe has been reported to be a cholesterol...

Tubastatin A | 27663-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: N/A Product Type: Inhibitor ...

OG-L002 | 27635-1 | Gentaur US, UK & Europe Disrtribition Category: Demethylase/Inhibitors / Activators Application: N/A Background: N/A Description: N/A Product Type: Inhibitor ...

C646 | 27613-1 | Gentaur US, UK & Europe Disrtribition Category: Acetyltransferase/Inhibitors / Activators Application: N/A Background: C646 binds to p300 as the Z-isomer forming hydrogen...

Levodopa | 79792 | Gentaur US, UK & Europe Disrtribition Category: Neuroscience/Inhibitors Application: N/A Background: N/A Description: Levodopa is a dopamine precursor that is being...

Carbidopa | 79791 | Gentaur US, UK & Europe Disrtribition Category: Neuroscience/Inhibitors Application: N/A Background: N/A Description: Carbidopa is a decarboxylase inhibitor used in...

Epacadostat (INCB024360) | 27339-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Immunotherapy Application: N/A Background: N/A Description: Epacadostat...

Epacadostat (INCB024360) | 27339-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Immunotherapy Application: N/A Background: N/A Description: Epacadostat...

INCB024360 Analog | 27338-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Immunotherapy Application: N/A Background: N/A Description: INCB024360 analog is an...

INCB024360 Analog | 27338-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Immunotherapy Application: N/A Background: N/A Description: INCB024360 analog is an...

NLG919 | 27337-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Immunotherapy Application: N/A Background: N/A Description: NLG919 is an orally available potent...

NLG919 | 27337-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Immunotherapy Application: N/A Background: N/A Description: NLG919 is an orally available potent...

(+)-JQ1 | 27400 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: N/A Description: (+)-JQ1 is a specific inhibitor of the...

1,5-Isoquinolinediol | 27310 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: N/A Description: PARP1 Inhibitor Product Type: ...

Ruxolitinib, Phosphate | 27059-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: Ruxolitinib, also known as...

Ruxolitinib, Phosphate | 27059-1 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: Ruxolitinib, also known as...

SMI-4a | 27774-1 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: The serine/threonine Pim kinases have been suggested to promote the...

Alvespimycin HCl (17-DMAG) | 27730-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: Alvespimycin hydrochloride is...

Droxinostat | 27620-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Droxinostat has shown a potent action against HDAC3,...

Cisplatin | 27744 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Cisplatin induces cytotoxicity by interaction with DNA to form...

Vardenafil HCl Trihydrate | 27776-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Vardenafil is frequently used in...

EPZ005687 | 27624-1 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ005687 is a potent inhibitor of EZH2, an...

Rolipram | 27005 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Rolipram is a selective, cell...

UPF 1069 | 27665-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: N/A Description: UPF 1069, a derivative of isoquinolinone,...

Tenovin-1 | 27660-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Tenovin-1, a small molecule discovered by a cell-based...

SGI-1776 free base | 27651-1 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: According to preliminary results from studies treating...

3-aminobenzamide | 79888-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: 3-aminobenzamide can sensitize cells to...

Cilomilast | 27742-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Cilomilast, also known as...

Apoptosis Inhibitor | 27734-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: Apoptosis Inhibitor is a cell-permeable...

S- (+)-Rolipram | 27648-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Rolipram is a racemic drug that increases...

PI-103 | 27502-1 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: PI-103 is a multi-targeted inhibitor of PI3K for...

P005091 | 27767-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: N/A Background: USP7, known as...

UNC669 | 27664-1 | Gentaur US, UK & Europe Disrtribition Category: Methyl-lysine Reader/Inhibitors / Activators Application: N/A Background: N/A Description: UNC669 is a potent and...

Rocilinostat (ACY-1215) | 27644-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Rocilinostat, also...

Posaconazole | 27639-1 | Gentaur US, UK & Europe Disrtribition Category: Demethylase/Inhibitors / Activators Application: N/A Background: Posaconazole, also known as SCH 56592 or Noxafil, is...

Donepezil HCl | 27619-1 | Gentaur US, UK & Europe Disrtribition Category: Metabolic Enzymes/Inhibitors Application: N/A Background: Donepezil HCl is a piperidine-class AChE inhibitor...

Belinostat (PXD101) | 27608-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Belinostat has been found to significantly...

Vinpocetine | 27778-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Vinpocetine, also known as...

NSC697923 | 27765-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: N/A Background: NSC697923 selectively inhibits PMA-induced NF-?B...

MC1568 | 27761-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: MC1568, a derivative of (Aryloxopropenyl)pyrrolyl...

Tubastatin A | 27663-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: N/A Product Type: Inhibitor ...

Tadalafil | 27657-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Tadalafil is a small-molecule inhibitor of...

Rucaparib (AG-014699,PF-01367338) | 27647-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: Rucaparib, also named as AG-014699 or...

ME0328 | 27634-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: N/A Description: ME0328 is a potent and selective PARP...

Irsogladine | 27754 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Irsogladine is a selective PDE4 inhibitor that...

KY 02111 | 27759-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: N/A Description: Promotes differentiation of human ESCs and...