Inhibitor

b-AP15 (NSC-687852) | 27701-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Suitable for validation studies of the deubiquitinating activities of the 19S regulatory particle as a drug target,...

Z-VEID-FMK | 27669-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VEID is the specific recognition sequence for caspase-6/Mch2. Caspase 6 is only one of at least three effector caspases, the...

Z-VDVAD-FMK | 27668-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VDVAD has been shown to be a preferred cleavage site for caspase-2. Caspase 2 is a very versatile caspase with multiple...

Q-VD(OMe)-OPh | 27640-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Q-VD-OPh is a broad spectrum caspase inhibitor that provides a cost effective, non toxic, and highly speci?c means of...

JW 55 | 27633-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: Inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased...

Apicidin | 27329 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC3 &HDAC6 Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

Pyroxamide | 27328 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC Inhibitor Product Type: Inhibitor Shippement Condition: gel packs

SMI-4a | 27774-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: The serine/threonine Pim kinases have been suggested to promote the activity of the rapamycin-sensitive mammalian target of...

UPF 1069 | 27665-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: N/A Description: UPF 1069, a derivative of isoquinolinone, is a potent and selective inhibitor of poly-(ADP-ribose)...

VER 155008 | 27777-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: VER 155008 is a potent inhibitor of heat shock protein 70 (Hsp70) family of chaperones, which have been...

Rocilinostat (ACY-1215) | 27644-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Rocilinostat, also known as ACY-1215, is a selective HDAC6 inhibitor with...

AG-14361 | 27602-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: A 17-hour exposure of A549 cells to 0.4 µM AG14361 does not change the expression of the 6800 genes. Thus, although 0...

ND-630 | 27071-2 | Gentaur US, UK & Europe Disrtribition Category: Metabolic Enzymes/Inhibitors Application: N/A Background: N/A Description: ND-630 (NDI 010976) is a highly specific, reversible inhibitor of ACC1 (IC50 = 2 nM) and ACC2 (IC50...

Lactacystin | 27705 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of the 20S proteasome. Background: N/A Description: Lactacystin is a cell-permeable, potent and...

CHS-828 | 27333 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: N/A Description: NAMPT Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

Salermide | 27324 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: SIRT1 and 2 Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

AMI-1 (sodium salt) | 27307 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: N/A Description: PRMT1,3,4 &6 Inhibitor Product Type: Inhibitor Shippement Condition: ...

PYR-41 | 27716-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of E1 ubiquitin conjugating enzymes Background: N/A Description: PYR-41 is a cell permeable,...

GSK256066 | 27751-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: GSK256066 is a selective PDE4 inhibitor with an exceptionally high-affinity and...

Roflumilast | 27645-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: The enzyme PDE-4 is found mainly in inflammatory cells, and Roflumilast acts as a selective,...

PFI-1 | 27332 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: N/A Description: BRD2 and BRD4 Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

Ac-DEVD-CMK | 27315 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: Caspase-3 Inhibitor Product Type: Inhibitor Shippement Condition: room temp or gel packs

VX-765 | 27779-3 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VX-765 is an orally-absorbed pro-drug of VRT-043198, a potent and selective inhibitor of ICE/caspase-1 sub-family caspases...

PF-2545920 | 27637-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: PDE10A is highly expressed in the medium spiny neurons of the striatum and regulates both cGMP and cAMP...

BMN-673 8R,9S | 27610-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with...

Wnt-C59 | 27780-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: Wnt-C59 prevents palmitoylation of Wnt proteins by Porcupine (a membrane-bound O-acyltransferase), thereby blocking...

P005091 | 27767-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: N/A Background: USP7, known as herpes-associated-ubiquitin-specificprotease (HAUSP), is a deubiquitylating enzyme that...

ICG 001 | 27752-3 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: ICG001 selectively inhibits colon carcinoma cell lines (SW480 and HCT-116 cells) but not normal colonic epithelial...

Alvespimycin HCl (17-DMAG) | 27730-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: Alvespimycin hydrochloride is the hydrochloride salt of alvespimycin, an analogue of...

ITF 2357 | 27327 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

KY 02111 | 27759-3 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: N/A Description: Promotes differentiation of human ESCs and iPSCs into cardiomyocytes. Induces downregulation of...

Z-DQMD-FMK | 27666-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Z-DQMD-FMK is a potent cell-permeable inhibitor of caspase-3. Researchers have shown that expression of a short peptide of 15...

Belinostat (PXD101) | 27608-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Belinostat has been found to significantly increase the acetylation of histones H3 and H4 and exerts...

PI-103 | 27502-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: PI-103 is a multi-targeted inhibitor of PI3K for p110, p110, p110 , and p110 with reported IC50...

XL-888 | 27781-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: X-ray crystallographic analysis reveals that the XL-888 binds to HSP90 through the formation of H-bonding...

NSC-632839 | 27709-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for non-specific inhibition of ubiquitin-like isopeptidases for cell biology and drug discovery studies. ...

Caspase-3/7 Inhibitor I | 27741-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Selectivity for caspases-3 and 7 involves unique hydrophobic residues in the S2 pocket surrounding the catalytic...

PS-341 (MG-341) | 27715-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for as a potent, cell permeable proteasome inhibitor for drug discovery research. Background: N/A ...

Aclacinomycin A | 27700 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: Useful for as a potent, cell permeable proteasome inhibitor for drug discovery research. Background: N/A Description: ...

CP 80633 | 27301 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: CP 80633 is a selective inhibitor of PDE4, which does not display significant isozyme...

JNJ-26481585 | 27632-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Quisinostat, also known asJNJ-26481585, is an orally bioavailable, second-generation, hydroxamic acid-based...

Donepezil HCl | 27619-2 | Gentaur US, UK & Europe Disrtribition Category: Metabolic Enzymes/Inhibitors Application: N/A Background: Donepezil HCl is a piperidine-class AChE inhibitor containing an N-benzylpiperdine and an indanone moiety, which...

CUDC-907 | 27616-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: CUDC-907 has a long half-life in murine tumors. CUDC-907 induces apoptosis and inhibits cancer cell...

MLN-4924 | 27708 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of the NEDD8 and NEDD8-dependent pathways. Background: N/A Description: Containing the active...

Splitomicin | 27330 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC Inhibitor Product Type: Inhibitor Shippement Condition: room temp.

Pimobendan | 27638-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 µM. Product Type: ...

AR-42 (OSU-HDAC42) | 27603-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: AR-42 induces histone H3 acetylation, α-tubulin acetylation and p21 up-regulation, which have been...

OTX-015 | 27636-1 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific sites, including...

CHIR-99021 (CT99021) HCl | 27615-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: Hydrochloride salt of CHIR 99021, a highly selective glycogen synthase kinase-3...

Thiazovivin | 78506-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Inhibitor Application: N/A Background: N/A Description: ROCK inhibitor. Increases the survival of cells differentiated from induced pluripotent stem cells upon...

Thiazovivin | 78506-1 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Inhibitor Application: N/A Background: N/A Description: ROCK inhibitor. Increases the survival of cells differentiated from induced pluripotent stem cells upon...

CHIR-99021 (CT99021) | 27614-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: CHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor that can...

Boc-D-FMK | 27611-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Boc-D-FMK is a cell-permeable broad-spectrum caspase inhibitor that fully inhibits the pro-apoptotic effect of tumor necrosis...

DBeQ | 27703-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: Useful for the study of the ubiquitin-dependent and endoplasmic reticulum-associated degradation pathway (p97 ATPase) Background: N/A ...

Z-FA-FMK | 27667-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: N/A Product Type: Inhibitor Shippement Condition: Room temp. (continental US) or gel packs

Sirtinol | 27652-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Unlike TSA, Sirtinol does not inhibit class I and class II HDACs, indicating that it is a selective sirtuin...

EPZ005687 | 27624-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ005687 is a potent inhibitor of EZH2, an enzymatic subunit of polycomb repressive complex 2 (PRC2)...

Ganetespib (STA-9090) | 27750-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: N/A Description: Ganetespib (also known as STA-9090) is a potent small-molecule inhibitor of heat...

EPZ-6438 | 27626-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ-6438 competitively binds to the S-adenosylmethionine (SAM) binding site of EZH2 and also...

Pracinostat (SB939) | 27771-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor...

AT13387 | 27736-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: N/A Description: AT13387, discovered by a high-throughput x-ray craystallography fragment-based platform, is a...

PYR-41 | 27716-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of E1 ubiquitin conjugating enzymes Background: N/A Description: PYR-41 is a cell permeable,...

UNC0224 | 27303 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: N/A Description: UNC0224 is a potent and selective inhibitor of G9a, a histone methyltransferase (HMT)...

SMER3 | 27718-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for the inhibition of SCFMET30 in cell-based or in vitro assays. Background: N/A Description: Small Molecule Enhancer...

Nutlin-3 | 27711 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: Useful as an MDM2 antagonist, as a p53 activator and as an apoptosis inducer. Background: N/A Description: Cis-imidazoline analog...

NVP-BEP800 | 27766-1 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: NVP-BEP800 binds to the N-terminal ATP-binding pocket of Hsp90. Hsp90 is a ubiquitously expressed molecular...

LAQ824 (NVP-LAQ824,Dacinostat) | 27760-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: A recent study shows that LAQ824 induces chromatin changes at the level of the IL-10 gene...

IPI-504 (Retaspimycin hydrochloride) | 27753-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: Cancer cells depend on the Hsp90 chaperone to maintain many proteins critical for...

Apremilast (CC-10004) | 27735-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Apremilast, also known as CC-10004, is a novel and potent small-molecule...

S- (+)-Rolipram | 27648-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Rolipram is a racemic drug that increases brain cAMP availability by inhibiting phosphodiesterase...

PF-2545920 | 27637-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: PDE10A is highly expressed in the medium spiny neurons of the striatum and regulates both cGMP and cAMP...

Droxinostat | 27620-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Droxinostat has shown a potent action against HDAC3, HDAC6, and HDAC8 which are pyrimidyl-hydroxamic...

A-966492 | 27601-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: A-966492 is one of the most potent PARP inhibitors. A-966492 displays excellent potency against the PARP-1 enzyme with...

MDBN | 27707 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for cell-based or in vitro characterization of p97/valosin-containing protein (VCP)/cdc48 function. Background: N/A ...

TCID | 27720-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for cell-based and in vitro studies of UCH-L3 function. Background: N/A Description: A potent and selective inhibitor...

Telotristat | 27340 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: N/A Description: Telotristat is the active metabolite of LX1606 (Telotristat etiprate), which is an...

3-aminobenzamide | 79888-3 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: 3-aminobenzamide can sensitize cells to radiation in vitro by inhibiting the repair of DNA damage,...

XL-888 | 27781-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: X-ray crystallographic analysis reveals that the XL-888 binds to HSP90 through the formation of H-bonding...

Ganetespib (STA-9090) | 27750-1 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: N/A Description: Ganetespib (also known as STA-9090) is a potent small-molecule inhibitor of heat...

Anagrelide HCl | 27732-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Anagrelide is a FDA-approved drug for the treatment of essential thrombocythemia. It is originally...

Celastrol | 27702-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of NF-κappa-B-dependent pathways and inhibition of 20S proteasome chymotrypsin-like activity. ...

TAME-HCL | 27719 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of the anaphase-promoting complex (APC)-ubiquitin ligase. Background: N/A Description: N/A Product...

SL-01 | 27717 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for the inhibition of p53-MDM2 interactions. Background: N/A Description: Inhibits the p53-MDM2 interaction (20 µM)...

RGFP966 | 27643-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: RGFP966 is a slow-on/slow-off, competitive tight-binding HDAC inhibitor. RGFP966 treatment on two CTCL cell...

Parthenolide | 27768-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Parthenolide is a sesquiterpene lactone, a class of naturally occurring plant terpenoids, and the active...

P22077 | 27712-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of USP7 and USP47 activity. Background: N/A Description: P22077 is a cell permeable inhibitor of the...

Entacapone | 27621-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: N/A Description: Entacapone is a second-generation catechol-O-methyltransferase (COMT) inhibitor...

I-CBP112 (Hydrochloride) | 27336 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: N/A Description: I-CBP112 (Hydrochloride) is a selective inhibitor of cAMP...

Tenovin-1 | 27660-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Tenovin-1, a small molecule discovered by a cell-based screen, is a bio-active activator of p53 that elevates...

SGI-1776 free base | 27651-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: According to preliminary results from studies treating prostate cancer cells, SGI-1776 dose-dependently reduces...

JNJ-26481585 | 27632-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Quisinostat, also known asJNJ-26481585, is an orally bioavailable, second-generation, hydroxamic acid-based...

EPZ5676 | 27625-1 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ5676 is a potent inhibitor of DOT1L histone methyltransferase that, according to X-ray crystallographic...

CUDC-907 | 27616-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: CUDC-907 has a long half-life in murine tumors. CUDC-907 induces apoptosis and inhibits cancer cell...

NSC-66811 | 27710 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for cell-based studies of MDM2 and p53 function Background: N/A Description: N/A Product Type: ...

PCI-24781 (CRA-024781) | 27769-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: PCI-24781 is a pan-HDAC inhibitor that shows antitumor activity in vitro and in vivo...

BIBR 1532 | 27740-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis/Inducer Application: N/A Background: It has been reported that BIBR 1532 inhibited the reverse transcriptase of telomerase, hTERT, and shortened the length of the...

I-BET-762 | 27630-1 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific sites,...

Apoptosis Inhibitor | 27734-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: Apoptosis Inhibitor is a cell-permeable inhibitor of apoptosis induction. It does not directly...

WP1130 | 27722-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Suitable for cell-based studies of USP function. Background: N/A Description: A partially-selective, cell permeable DUB...

PR-619 | 27714-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for non-specific inhibition of ubiquitin-like isopeptidases for cell biology and drug discovery studies. Background: ...