Inhibitor

b-AP15 (NSC-687852) | 27701-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Suitable for validation studies of the deubiquitinating...

Z-VEID-FMK | 27669-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VEID is the specific recognition sequence for caspase-6/Mch2. Caspase...

Z-VDVAD-FMK | 27668-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VDVAD has been shown to be a preferred cleavage site for caspase-2...

Q-VD(OMe)-OPh | 27640-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Q-VD-OPh is a broad spectrum caspase inhibitor that provides a cost...

JW 55 | 27633-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: Inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2)...

Apicidin | 27329 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC3 &HDAC6 Inhibitor Product...

Pyroxamide | 27328 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC Inhibitor Product Type: ...

SMI-4a | 27774-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: The serine/threonine Pim kinases have been suggested to promote the...

UPF 1069 | 27665-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: N/A Description: UPF 1069, a derivative of isoquinolinone,...

VER 155008 | 27777-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: VER 155008 is a potent inhibitor of heat shock...

Rocilinostat (ACY-1215) | 27644-3 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: Rocilinostat, also...

AG-14361 | 27602-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: A 17-hour exposure of A549 cells to 0.4 µM AG14361 does not...

ND-630 | 27071-2 | Gentaur US, UK & Europe Disrtribition Category: Metabolic Enzymes/Inhibitors Application: N/A Background: N/A Description: ND-630 (NDI 010976) is a highly specific,...

Lactacystin | 27705 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of the 20S proteasome. Background: N/A ...

CHS-828 | 27333 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: N/A Description: NAMPT Inhibitor Product Type: ...

Salermide | 27324 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: SIRT1 and 2 Inhibitor Product Type:...

AMI-1 (sodium salt) | 27307 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: N/A Description: PRMT1,3,4 &6...

PYR-41 | 27716-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of E1 ubiquitin conjugating enzymes Background: ...

GSK256066 | 27751-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: GSK256066 is a selective PDE4...

Roflumilast | 27645-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: The enzyme PDE-4 is found mainly in...

PFI-1 | 27332 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: N/A Description: BRD2 and BRD4 Inhibitor Product Type: ...

Ac-DEVD-CMK | 27315 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: Caspase-3 Inhibitor Product Type: Inhibitor ...

VX-765 | 27779-3 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: VX-765 is an orally-absorbed pro-drug of VRT-043198, a potent and...

PF-2545920 | 27637-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: PDE10A is highly expressed in the medium spiny...

BMN-673 8R,9S | 27610-1 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: BMN-673 is an orally bioavailable inhibitor of the nuclear...

Wnt-C59 | 27780-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: Wnt-C59 prevents palmitoylation of Wnt proteins by Porcupine (a...

P005091 | 27767-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: N/A Background: USP7, known as...

ICG 001 | 27752-3 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: ICG001 selectively inhibits colon carcinoma cell lines (SW480...

Alvespimycin HCl (17-DMAG) | 27730-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: Alvespimycin hydrochloride is...

ITF 2357 | 27327 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC Inhibitor Product Type: ...

KY 02111 | 27759-3 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Other Application: N/A Background: N/A Description: Promotes differentiation of human ESCs and...

Z-DQMD-FMK | 27666-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Z-DQMD-FMK is a potent cell-permeable inhibitor of caspase-3...

Belinostat (PXD101) | 27608-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Belinostat has been found to significantly...

PI-103 | 27502-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: PI-103 is a multi-targeted inhibitor of PI3K for...

XL-888 | 27781-1 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: X-ray crystallographic analysis reveals that the...

NSC-632839 | 27709-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for non-specific inhibition of ubiquitin-like isopeptidases for...

Caspase-3/7 Inhibitor I | 27741-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Selectivity for caspases-3 and 7 involves unique...

PS-341 (MG-341) | 27715-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for as a potent, cell permeable proteasome inhibitor for...

Aclacinomycin A | 27700 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: Useful for as a potent, cell permeable proteasome inhibitor for drug...

CP 80633 | 27301 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: CP 80633 is a selective...

JNJ-26481585 | 27632-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Quisinostat, also known asJNJ-26481585, is an orally...

Donepezil HCl | 27619-2 | Gentaur US, UK & Europe Disrtribition Category: Metabolic Enzymes/Inhibitors Application: N/A Background: Donepezil HCl is a piperidine-class AChE inhibitor...

CUDC-907 | 27616-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: CUDC-907 has a long half-life in murine tumors. CUDC-907...

MLN-4924 | 27708 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of the NEDD8 and NEDD8-dependent pathways. ...

Splitomicin | 27330 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: N/A Description: HDAC Inhibitor Product Type: ...

Pimobendan | 27638-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Pimobendan is a selective...

AR-42 (OSU-HDAC42) | 27603-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: AR-42 induces histone H3 acetylation,...

OTX-015 | 27636-1 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the targeting of...

CHIR-99021 (CT99021) HCl | 27615-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: Hydrochloride salt of CHIR...

Thiazovivin | 78506-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Inhibitor Application: N/A Background: N/A Description: ROCK inhibitor. Increases the survival of cells...

Thiazovivin | 78506-1 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Inhibitor Application: N/A Background: N/A Description: ROCK inhibitor. Increases the survival of cells...

CHIR-99021 (CT99021) | 27614-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: N/A Description: CHIR-99021 is a highly specific...

Boc-D-FMK | 27611-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: Boc-D-FMK is a cell-permeable broad-spectrum caspase inhibitor that...

DBeQ | 27703-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: Useful for the study of the ubiquitin-dependent and endoplasmic...

Z-FA-FMK | 27667-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: N/A Product Type: Inhibitor Shippement...

Sirtinol | 27652-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Unlike TSA, Sirtinol does not inhibit class I and class...

EPZ005687 | 27624-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ005687 is a potent inhibitor of EZH2, an...

Ganetespib (STA-9090) | 27750-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: N/A Description: Ganetespib (also known as...

EPZ-6438 | 27626-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ-6438 competitively binds to the...

Pracinostat (SB939) | 27771-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Pracinostat (SB939) is an orally...

AT13387 | 27736-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: N/A Description: AT13387, discovered by a high-throughput...

PYR-41 | 27716-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of E1 ubiquitin conjugating enzymes Background: ...

UNC0224 | 27303 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: N/A Description: UNC0224 is a potent and selective...

SMER3 | 27718-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for the inhibition of SCFMET30 in cell-based or in vitro assays. ...

Nutlin-3 | 27711 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: Useful as an MDM2 antagonist, as a p53 activator and as an apoptosis inducer. ...

NVP-BEP800 | 27766-1 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: NVP-BEP800 binds to the N-terminal ATP-binding pocket of...

LAQ824 (NVP-LAQ824,Dacinostat) | 27760-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: A recent study shows that LAQ824...

IPI-504 (Retaspimycin hydrochloride) | 27753-2 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: Cancer cells depend on the...

Apremilast (CC-10004) | 27735-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: N/A Description: Apremilast, also...

S- (+)-Rolipram | 27648-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Rolipram is a racemic drug that increases...

PF-2545920 | 27637-1 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: PDE10A is highly expressed in the medium spiny...

Droxinostat | 27620-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Droxinostat has shown a potent action against HDAC3,...

A-966492 | 27601-2 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: A-966492 is one of the most potent PARP inhibitors. A-966492...

MDBN | 27707 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for cell-based or in vitro characterization of p97/valosin-containing...

TCID | 27720-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for cell-based and in vitro studies of UCH-L3 function. Background:...

Telotristat | 27340 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: N/A Description: Telotristat is the active...

3-aminobenzamide | 79888-3 | Gentaur US, UK & Europe Disrtribition Category: PARP/Inhibitors / Activators Application: N/A Background: 3-aminobenzamide can sensitize cells to...

XL-888 | 27781-2 | Gentaur US, UK & Europe Disrtribition Category: Inhibitors / Activators/Metabolic Enzymes Application: N/A Background: X-ray crystallographic analysis reveals that the...

Ganetespib (STA-9090) | 27750-1 | Gentaur US, UK & Europe Disrtribition Category: Protease/Inhibitors / Activators Application: N/A Background: N/A Description: Ganetespib (also known as...

Anagrelide HCl | 27732-2 | Gentaur US, UK & Europe Disrtribition Category: Phosphodiesterase/Inhibitors / Activators Application: N/A Background: Anagrelide is a FDA-approved drug for the...

Celastrol | 27702-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of NF-κappa-B-dependent pathways and inhibition...

TAME-HCL | 27719 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of the anaphase-promoting complex (APC)-ubiquitin...

SL-01 | 27717 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for the inhibition of p53-MDM2 interactions. Background: N/A ...

RGFP966 | 27643-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: RGFP966 is a slow-on/slow-off, competitive tight-binding...

Parthenolide | 27768-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Parthenolide is a sesquiterpene lactone, a class of...

P22077 | 27712-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for inhibition of USP7 and USP47 activity. Background: N/A ...

Entacapone | 27621-2 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: N/A Description: Entacapone is a...

I-CBP112 (Hydrochloride) | 27336 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: N/A Description: I-CBP112...

Tenovin-1 | 27660-2 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Tenovin-1, a small molecule discovered by a cell-based...

SGI-1776 free base | 27651-2 | Gentaur US, UK & Europe Disrtribition Category: Kinase/Kinase Inhibitors Application: N/A Background: According to preliminary results from studies treating...

JNJ-26481585 | 27632-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: Quisinostat, also known asJNJ-26481585, is an orally...

EPZ5676 | 27625-1 | Gentaur US, UK & Europe Disrtribition Category: Methyltransferase/Inhibitors / Activators Application: N/A Background: EPZ5676 is a potent inhibitor of DOT1L histone...

CUDC-907 | 27616-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: CUDC-907 has a long half-life in murine tumors. CUDC-907...

NSC-66811 | 27710 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for cell-based studies of MDM2 and p53 function Background: N/A...

PCI-24781 (CRA-024781) | 27769-1 | Gentaur US, UK & Europe Disrtribition Category: Deacetylase/Inhibitors / Activators Application: N/A Background: PCI-24781 is a pan-HDAC inhibitor that...

BIBR 1532 | 27740-1 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis/Inducer Application: N/A Background: It has been reported that BIBR 1532 inhibited the reverse transcriptase...

I-BET-762 | 27630-1 | Gentaur US, UK & Europe Disrtribition Category: Bromodomain/Inhibitors / Activators Application: N/A Background: Bromodomains have an important role in the targeting of...

Apoptosis Inhibitor | 27734-2 | Gentaur US, UK & Europe Disrtribition Category: Apoptosis Inhibitor Application: N/A Background: N/A Description: Apoptosis Inhibitor is a cell-permeable...

WP1130 | 27722-2 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Suitable for cell-based studies of USP function. Background: N/A ...

PR-619 | 27714-1 | Gentaur US, UK & Europe Disrtribition Category: Ubiquitination/Inhibitors / Activators Application: Useful for non-specific inhibition of ubiquitin-like isopeptidases for...