Recombinant Rhesus macaque CD155/PVR/NECL5 Protein (His Tag) | PKSQ050071

Recombinant Rhesus macaque CD155/PVR/NECL5 Protein (His Tag) | PKSQ050071 | Gentaur US, UK & Europe Disrtribition

Synonyms: Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS

Active Protein: N/A

Activity: Recombinant Rhesus macaque NECL5 is produced by our Mammalian expression system and the target gene encoding Met 1-Asn 343 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Rhesus macaque NECL5 is produced by our Mammalian expression system and the target gene encoding Met 1-Asn 343 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-His

Species: Rhesus macaque

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 35.4 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains.

Research Area: N/A