Recombinant Human CD155/PVR/NECL5 Protein (Fc Tag) | PKSH033562

Recombinant Human CD155/PVR/NECL5 Protein (Fc Tag) | PKSH033562 | Gentaur US, UK & Europe Disrtribition

Synonyms: Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS

Active Protein: N/A

Activity: Recombinant Human NECL5 is produced by our Mammalian expression system and the target gene encoding Trp21-Asn343 is expressed with a Fc tag at the C-terminus.

Protein Construction: Recombinant Human NECL5 is produced by our Mammalian expression system and the target gene encoding Trp21-Asn343 is expressed with a Fc tag at the C-terminus.

Fusion Tag: C-Fc

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 62.2 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV); an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains; a transmembrane segment; and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α; β; γ; and δ) with identical extracellular domains.

Research Area: Microbiology