Description
Recombinant Human CD155/PVR/NECL5 Protein (mFc Tag) | PKSH033561 | Gentaur US, UK & Europe Disrtribition
Synonyms: Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS
Active Protein: N/A
Activity: Recombinant Human NECL5 is produced by our Mammalian expression system and the target gene encoding Trp21-Asn343 is expressed with a mFc tag at the C-terminus.
Protein Construction: Recombinant Human NECL5 is produced by our Mammalian expression system and the target gene encoding Trp21-Asn343 is expressed with a mFc tag at the C-terminus.
Fusion Tag: C-mFc
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 61.7 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV); an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains; a transmembrane segment; and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α; β; γ; and δ) with identical extracellular domains.
Research Area: Microbiology
