NF-κB-Luciferase Reporter (Luc) - Jurkat Cell Line | 60651

NF-κB-Luciferase Reporter (Luc) - Jurkat Cell Line | 60651 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Cell Line

Application: The NF-κB-luciferase/Jurkat cell line is suitable for monitoring the activity of NF-kB signaling in response to stimulant, and establishing cell-based screens for inhibitors that target specific NF-κB stimulating molecules.

Background: N/A

Description: NF-κB luciferase reporter construct is stably integrated into the genome of Jurkat T- cells. The firefly luciferase gene is controlled by 4 copies of NF-kB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene.

Product Type: Cell Line

Shippement Condition: -80°C