Description
NF-κB-Luciferase Reporter (Luc) - Jurkat Cell Line | 60651 | Gentaur US, UK & Europe Disrtribition
Category: Immunotherapy/Cell Line
Application: The NF-κB-luciferase/Jurkat cell line is suitable for monitoring the activity of NF-kB signaling in response to stimulant, and establishing cell-based screens for inhibitors that target specific NF-κB stimulating molecules.
Background: N/A
Description: NF-κB luciferase reporter construct is stably integrated into the genome of Jurkat T- cells. The firefly luciferase gene is controlled by 4 copies of NF-kB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene.
Product Type: Cell Line
Shippement Condition: -80°C
