Claudin-9 CHO Cell Line | 78687

Claudin-9 CHO Cell Line | 78687 | Gentaur US, UK & Europe Disrtribition

Category: Cell Signaling Pathway/Cell Line

Application: • Screen and validate antibodies against claudin-9 for drug discovery and research. • Screen for compounds that regulate or inhibit claudin-9 signaling in a cellular context. • Perform binding assays to screen for potential claudin-9 ligands.

Background: Claudins are integral membrane proteins and major components of tight junction strands that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Claudin-9 is one of the 27 members of the Claudin family. Diseases associated with Claudin-9 include deafness, autosomal recessive 116, and Hepatitis C viral infection for which it acts as a co-receptor for viral entry

Description: Recombinant clonal CHO cell line stably expressing full-length human claudin-9 (CLDN9 gene accession number NM_020982).  Surface expression of claudin-9 was confirmed by flow cytometry. The stable clonal cell line was selected for high levels of claudin-9 expression compared to the parental CHO-K1 cell line.

Product Type: Cell Line

Shippement Condition: -80°C