AAV5 Luciferase | 78456

AAV5 Luciferase | 78456 | Gentaur US, UK & Europe Disrtribition

Category: Cell Signaling/AAV virus

Application: Use as a positive control for transduction Optimize transduction assays and track protein expression over time

Background: N/A

Description: Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is effective at mediating gene transfer into human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for both mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8. These AAV particles constitutively express the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter. AAV transduction efficiency can easily be verified by measurement of luciferase activity.

Product Type: Viral Tools

Shippement Condition: -80°C