AAV5 ZsGreen | 78447

AAV5 ZsGreen | 78447 | Gentaur US, UK & Europe Disrtribition

Category: Viral Tools/AAV

Application: Use as a positive control for transduction Optimize transduction assays and track expression over time

Background: N/A

Description: Adeno-Associated Virus Serotype 5 (AAV5) differs from other parvovirus serotypes according to serological and DNA hybridization data, and AAV5 also uses different inverted terminal repeats (ITRs) compared to other AAV serotypes. AAV5 is the most efficient vector for transducing sensory neurons and is good at mediating gene transfer to human and murine airway epithelia. In addition, AAV5 vectors show a higher tropism for mouse and human dendritic cells than AAV1, AAV2, AAV7, or AAV8. These AAV5 particles constitutively express ZsGreen under a CMV promoter. ZsGreen is a human codon-optimized variant of the green fluorescent protein isolated from reef coral (Zoanthus sp). It has been engineered for higher expression in mammalian cells and is up to four times brighter than enhanced GFP (eGFP). ZsGreen expression and transduction efficiency can easily be verified and optimized by fluorescence microscopy or flow cytometry. ZsGreen has an excitation wavelength of 493 nm and an emission wavelength of 505 nm.

Product Type: AAV virus

Shippement Condition: -80°C