Description
Recombinant beta Catenin Monoclonal Antibody | E-AB-81445 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat, Hamster
Host: Rabbit
Isotype: IgG
Application: WB, IHC-P
Research Area: Cancer, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells
Background: CTNNB1, also known as β-Catenin, is an evolutionarily conserved, multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs, CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
Lead Time: 7~10 days
Concentration: 300 μg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: N/A
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Dilution: WB 1:1000-1:2000 IHC 1:50-1:100
Conjugation: Unconjugated
Calculated Molecular Weight: 86kDa
Observed Molecular Weight: 86kDa
Clonality: Rabbit Monoclonal
