PIASg Antibody (PIAS4) | R31339

PIASg Antibody (PIAS4) | R31339 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB

Buffer: N/A

Limitation: This PIASg antibody is available for research use only.

Purity: Antigen affinity

Description: Protein inhibitor of activated STAT protein 4 (PIAS4) or Protein inhibitor of activated STAT protein gamma (PIASg or PIASy) is an enzyme that in humans is encoded by the PIAS4 gene. This gene is mapped to 19p13.3. This gene plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. PIASg functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This gene involved in gene silencing.

Immunogen: An amino acid sequence from the C-terminus of human E3 SUMO-protein ligase PIASg (HPELCKALVKEKLRLD) was used as the immunogen for this PIASg antibody (100% homologous in human, mouse and rat).

Storage: After reconstitution, the PIASg antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.