PAI-1 Reporter (Luc) - Mv1 Lu Cell Line | 60544

PAI-1 Reporter (Luc) - Mv1 Lu Cell Line | 60544 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Cell Line

Application: Monitor TGF-β signaling pathway activity.

Background: N/A

Description: PAI-1 Reporter (Luc)-Mv1 Lu cell line is designed for monitoring transforming growth factor β (TGF-β)-induced plasminogen activator inhibitor-1 (PAI-1) expression. Transforming growth factor-β (TGF-β) is a potent regulator of cellular differentiation, proliferation, migration, and protein expression. PAI-1 Reporter (Luc) -Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu (NBL-7) cells, showing TGF-β pathway response. This cell line is validated for the TGF-β response to the induction of PAI-1 gene expression through luciferase activity.

Product Type: Cell Line

Shippement Condition: -80°C