NF- κB Reporter (Luc) - THP-1 Cell Line | 79645

NF- κB Reporter (Luc) - THP-1 Cell Line | 79645 | Gentaur US, UK & Europe Disrtribition

Category: Cell Line/Reporter Cell Line & Cell-Based Assays

Application: • Monitor NF-κB signaling pathway activity. • Screen for activators or inhibitors of NF-κB signaling pathway.

Background: N/A

Description: The NF-κB reporter (Luc)-THP-1 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

Product Type: Cell line

Shippement Condition: -80°C