Description
NF- κB Reporter (Luc) - Raw 264.7 Cell line | 79978 | Gentaur US, UK & Europe Disrtribition
Category: Cell Signaling/Cell Line
Application: • Screen for activators or inhibitors of NF-κB signaling pathway.
• Screen for activators or inhibitors of RANKL/RANK pathway.
Background: N/A
Description: The NF-κB reporter (Luc)-Raw 264.7 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.
Product Type: Cell Line
Shippement Condition: -80°C
