Description
Catenin beta Monoclonal Antibody | E-AB-70230 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Application: WB, IHC
Research Area: Cancer, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells
Background: CTNNB1, also known as β-Catenin, is an evolutionarily conserved, multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs, CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
Lead Time: 7~10 days
Concentration: 420 μg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein corresponding to Mouse β-catenin
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:1000, IHC 1:100-1:500
Conjugation: Unconjugated
Calculated Molecular Weight: 92 kDa
Observed Molecular Weight: 92 kDa
Clonality: Monoclonal
