VEGF Receptor 2 Antibody / VEGFR2 / KDR | V8272SAF-100UG

VEGF Receptor 2 Antibody / VEGFR2 / KDR | V8272SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: DC101

Host Animal: Rat

Clonality: Monoclonal (rat origin)

Species Reactivity: Mouse

Application: WB, Neutralizing, Blocking, Inhibition

Buffer: N/A

Limitation: This VEGFR2 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

Immunogen: Recombinant full-length Mouse VEGFR2 protein was used as the immunogen for this VEGFR2 antibody.

Storage: Store the VEGFR2 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).