Unconjugated Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Complex Protein (Monomer, MALS verified) | HLM-H52H6-200ug

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SKU:
716-HLM-H52H6-200ug
Availability:
IN STOCK
Size:
200 ug
€928.00
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Description

Unconjugated Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Complex Protein (Monomer, MALS verified) | HLM-H52H6-200ug| Gentaur Distribution US, UK & Europe

The MAGE A4 antigen is a cancer-testis antigen and is expressed intracellularly in various solid tumor tissues, MAGE A4230-239 peptide (GVYDGREHTV) is a cytotoxic T lymphocyte (CTL) epitope presented by HLA-A2 The Human HLA-A*0201 MAGE-A4 (GVYDGREHTV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and GVYDGREHTV peptide of the MAGE-A4.

Source: Unconjugated Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Complex Protein (HLM-H52H6) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & GVYDGREHTV peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & GVYDGREHTV).

Format: Powder.

Tag: C-10×His & C-Avi.

Expression System: HEK293.

Expression Region: Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & GVYDGREHTV peptide.

Conjugate: Unconjugated.

Molecular Weight: 36.3 kDa and 11.7 kDa.

Characteristics: Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Complex Protein is produced by co-expression of HLA and B2M loaded with MAGE-A4 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™), and it is not biotinylated. The protein has a calculated MW of 36.3 kDa and 11.7 kDa. The protein migrates as 40-45 kDa and 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT

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