TSSK2, GST-tag | 40290

TSSK2, GST-tag | 40290 | Gentaur US, UK & Europe Disrtribition

Category: Kinase-Serine/Threonine/Protein

Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

Background: TSSK2 is an intronless serine-threonine kinase that was originally detected on mouse chromosome 16 (1). TSSK2 and TSSK1 share 72% overall amino acid identity and 83% identity in the kinase domain (2). Real-time PCR showed abundant TSSK2 expression in testis and lower levels in heart, brain, and placenta while Western blot analysis detected TSSK2 at the predicted molecular mass of 40 kDa in human sperm and testis. Co-immunoprecipitation and yeast 2-hybrid analysis show that TSSK2 can interact with a protein TSKS, that also acts as a substrate for this protein kinase.

Description: Recombinant human TSSK2, full length, with an N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system. The gene accession number is NM_053006.

Product Type: Protein

Shippement Condition: -80°C