Description
TRP1 / Tyrosinase-Related Protein-1 Antibody | V3519IHC-7ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Format: Purified
Clone: TYRP1/1986
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This TYRP1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Tyrosinase-Related Protein-1/TYRP1/TRP1 is a melanocyte-specific gene product involved in melanin synthesis. While mouse Tyrp1 possesses dihydroxyindole carboxylic acid oxidase activity, the function in human melanocytes is less clear. In addition to its role in melanin synthesis, Tyrp1 is involved in stabilizing of tyrosinase protein and modulating its catalytic activity. Tyrp1 is also involved in maintenance of melanosome structure and affects melanocyte proliferation and melanocyte cell death. [Wiki]
Immunogen: A recombinant human partial protein corresponding to amino acids 257-377 was used as the immunogen for the TYRP1 antibody.
Storage: Store the TYRP1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
