TRP1 / Tyrosinase-Related Protein-1 Antibody | V2916IHC-7ML

TRP1 / Tyrosinase-Related Protein-1 Antibody | V2916IHC-7ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Format: Purified

Clone: TYRP1/807

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This TYRP1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Immunogen: Recombinant full-length human protein was used as the immunogen for the TYRP1 antibody.

Storage: Store the TYRP1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).