TRP1 / Tyrosinase-Related Protein-1 Antibody | V3519-100UG

TRP1 / Tyrosinase-Related Protein-1 Antibody | V3519-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: TYRP1/1986

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA, IHC-P

Buffer: N/A

Limitation: This TYRP1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Tyrosinase-Related Protein-1/TYRP1/TRP1 is a melanocyte-specific gene product involved in melanin synthesis. While mouse Tyrp1 possesses dihydroxyindole carboxylic acid oxidase activity, the function in human melanocytes is less clear. In addition to its role in melanin synthesis, Tyrp1 is involved in stabilizing of tyrosinase protein and modulating its catalytic activity. Tyrp1 is also involved in maintenance of melanosome structure and affects melanocyte proliferation and melanocyte cell death. [Wiki]

Immunogen: A recombinant human partial protein corresponding to amino acids 257-377 was used as the immunogen for the TYRP1 antibody.

Storage: Store the TYRP1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).