Transferrin Receptor Antibody / TFRC / CD71 | V2881CF488-100T

Transferrin Receptor Antibody / TFRC / CD71 | V2881CF488-100T | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: CF488 Conjugate

Clone: TFRC/1059

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF

Buffer: N/A

Limitation: This CD71 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Immunogen: Recombinant human protein was used as the immunogen for the Transferrin Receptor / CD71 antibody.

Storage: Store the CD71 antibody at 2-8oC, protected from light.