Description
Transferrin Receptor Antibody / TFRC / CD71 | V2261CF488-100T | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: CF488 Conjugate
Clone: 66IG10
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF
Buffer: N/A
Limitation: This CD71 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Immunogen: Recombinant human protein was used as the immunogen for this Transferrin receptor / CD71 antibody.
Storage: Store the CD71 antibody at 2-8oC, protected from light.
