TNNI3 Polyclonal Antibody | E-AB-70275

TNNI3 Polyclonal Antibody | E-AB-70275 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB

Research Area: Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells

Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Lead Time: 7~10 days

Concentration: 140 μg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Cardiac Troponin I

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000

Conjugation: Unconjugated

Calculated Molecular Weight: 24 kDa

Observed Molecular Weight: 28 kDa

Clonality: Polyclonal