Synaptophysin Antibody | V9154-20UG

Synaptophysin Antibody | V9154-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: rSYP/6856

Host: Mouse

Clonality: Recombinant Mouse Monoclonal

Isotype: Mouse IgG1, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 2-4ug/ml

Application Note: Optimal dilution of the recombinant SYP antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: This recombinant mouse monoclonal antibody recognizes a protein of 38kDa that is identified as Synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

Immunogen: A portion of amino acids 224-313 was used as the immunogen for the recombinant SYP antibody.

Storage: Aliquot the recombinant SYP antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cytoplasm