Specificity Protein 1 Antibody / SP1 | RQ4532

Specificity Protein 1 Antibody / SP1 | RQ4532 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC-P, ICC, IF/ICC, ELISA

Buffer: N/A

Limitation: This SP1 antibody is available for research use only.

Purity: Antigen affinity

Description: Transcription factor Sp1, also known as 'Specificity protein 1' is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Immunogen: Amino acids 384-603 of the human protein were used as the immunogen for the SP1 antibody.

Storage: After reconstitution, the SP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.