Description
SOCS4 Antibody | F41736-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC, IF, WB, ELISA
Buffer: N/A
Limitation: This SOCS4 antibody is available for research use only.
Purity: Antigen affinity
Description: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]
Immunogen: A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody.
Storage: Aliquot the SOCS4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
