SOCS4 Antibody | F41736-0.08ML

SOCS4 Antibody | F41736-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, IF, WB, ELISA

Buffer: N/A

Limitation: This SOCS4 antibody is available for research use only.

Purity: Antigen affinity

Description: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]

Immunogen: A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody.

Storage: Aliquot the SOCS4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.