SARS-CoV-2 Spike RBD Protein, His Tag (BA.2/Omicron) (MALS verified) | SPD-C522g-100ug

SARS-CoV-2 Spike RBD Protein, His Tag (BA.2/Omicron) (MALS verified) | SPD-C522g-100ug| Gentaur Distribution US, UK & Europe

It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: SARS-CoV-2 Spike RBD, His Tag (BA.2/Omicron) (SPD-C522g) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2; GISAID clade: GRA; Nextstrain clade: 21L).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Arg 319 - Lys 537.

Conjugate: Unconjugated.

Molecular Weight: 26.7 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.7 kDa. The protein migrates as 33-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT