SARS-CoV-2 Spike RBD Protein, His Tag (BA.2.86/V483/Denmark) (MALS verified) | SPD-C5248-1mg

SARS-CoV-2 Spike RBD Protein, His Tag (BA.2.86/V483/Denmark) (MALS verified) | SPD-C5248-1mg| Gentaur Distribution US, UK & Europe

It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: SARS-CoV-2 Spike RBD Protein, His Tag (BA.2.86/V483/Denmark) (SPD-C5248) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (I332V, G339H, K356T, S371F, S373P, S375F, T376A, R403K, D405N, R408S, K417N, N440K, V445H, G446S, N450D, L452W, N460K, S477N, T478K, N481K, E484K, F486P, Q498R, N501Y, Y505H) ). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2.86/V483/Denmark).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Arg 319 - Lys 537.

Conjugate: Unconjugated.

Molecular Weight: 26.8 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.8 kDa. The protein migrates as 38-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT