Description
SARS-CoV-2 Spike RBD Protein, His Tag (BA.1.1/Omicron) (MALS verified) | SPD-C522j-100ug| Gentaur Distribution US, UK & Europe
It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Source: SARS-CoV-2 Spike RBD, His Tag (BA.1.1/Omicron) (SPD-C522j) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H) ). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.1.1; GISAID clade: GRA; Nextstrain clade: 21K).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Arg 319 - Lys 537.
Conjugate: Unconjugated.
Molecular Weight: 26.8 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.8 kDa. The protein migrates as 31-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
