Recombinant Vimentin Monoclonal Antibody | E-AB-81438

Recombinant Vimentin Monoclonal Antibody | E-AB-81438 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat, Hamster

Host: Rabbit

Isotype: IgG

Application: WB, IHC-P, IF

Research Area: Cancer, Developmental Biology, Neuroscience, Signal Transduction, Stem Cells

Background: Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10 (124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.

Lead Time: 7~10 days

Concentration: 300 μg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: N/A

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification: Affinity Purified

Dilution: WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 54kDa

Observed Molecular Weight: 54kDa

Clonality: Rabbit Monoclonal