Description
Recombinant Rhesus macaque CD27/TNFRSF7 Protein (Fc Tag) | PKSQ050077 | Gentaur US, UK & Europe Disrtribition
Synonyms: CD27 Antigen; CD27L Receptor; T-Cell Activation Antigen CD27; T14; Tumor Necrosis Factor Receptor Superfamily Member 7; CD27; CD27; TNFRSF7
Active Protein: N/A
Activity: Recombinant Rhesus macaque CD27 is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Rhesus macaque CD27 is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Rhesus macaque
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 46.5 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mMTris, 150mM NaCl, pH8.5.
Reconstitution: Please refer to the printed manual for detailed information.
Background: CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7，belongs to the TNF-receptor superfamily. CD27 is a single-pass type I membrane protein and exists as a homodimer form, containing three TNFR-Cys repeats. CD27 transduces signals that lead to the activation of NF-KappaB and MAPK8/JNK. CD27 is involved in regulating B-cell activation and immunoglobulin synthesis, binding to the ligand CD70. TRAF2 and TRAF5 have been shown to mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to CD27 and is thought to play a key role in the apoptosis. CD27 is required for generation and long-term maintenance of T cell immunity.
Research Area: N/A
