Recombinant Rhesus macaque CD160 Protein (Fc Tag) | PKSQ050081

Recombinant Rhesus macaque CD160 Protein (Fc Tag) | PKSQ050081 | Gentaur US, UK & Europe Disrtribition

Synonyms: CD160 antigen; CD160

Active Protein: N/A

Activity: Recombinant Rhesus macaque CD160 is produced by our Mammalian expression system and the target gene encoding Met1-Leu158 is expressed with a Fc tag at the C-terminus.

Protein Construction: Recombinant Rhesus macaque CD160 is produced by our Mammalian expression system and the target gene encoding Met1-Leu158 is expressed with a Fc tag at the C-terminus.

Fusion Tag: C-Fc

Species: Rhesus macaque

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 45 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+)peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and small intestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.

Research Area: N/A