Recombinant PI3 Kinase p85 alpha Monoclonal Antibody | E-AB-81435

Recombinant PI3 Kinase p85 alpha Monoclonal Antibody | E-AB-81435 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Rat, Hamster

Host: Rabbit

Isotype: IgG

Application: WB, IF

Research Area: Cancer, Metabolism, Immunology, Signal Transduction

Background: Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.

Lead Time: 7~10 days

Concentration: 300 μg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: N/A

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification: Affinity Purified

Dilution: WB 1:500-1:1000 IF 1:20-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 84kDa

Observed Molecular Weight: 84kDa

Clonality: Rabbit Monoclonal