Recombinant Nucleosome (E. coli-derived) | 52038

Recombinant Nucleosome (E. coli-derived) | 52038 | Gentaur US, UK & Europe Disrtribition

Category: Methyltransferase/Substrates

Application: Substrate for histone methyltransferase assays. Ideal for screening small molecular inhibitors of histone methyltransferases for drug discovery and HTS applications.

Background: N/A

Description: Human recombinant nucleosomes consisting of 147 bp DNA (PCR) and 2 molecules each of histones H2A (a.a. 2-130(end)), H2B (a.a. 2-126(end)), H3 (a.a. 2-137(end)), and H4 (a.a. 2-103(end)), expressed in an E. coli expression system. GenBank Accession Nos. are NM_033445, NM_003528, NM_003532, and NM_003548, respectively. Each histone protein has an N-terminal His-tag. Total histone MW = 113.8 kDa.

Product Type: Protein

Shippement Condition: -80°C