Recombinant Mouse Chromogranin-A/Chga protein (His Tag) | PKSM500000

Recombinant Mouse Chromogranin-A/Chga protein (His Tag) | PKSM500000 | Gentaur US, UK & Europe Disrtribition

Synonyms: beta Granin, betagranin (N-terminal fragment of chromogranin A), catestatin, CgA, CHG A, Chga, chromofungin, Chromogranin A, Chromogranin A parathyroid secretory protein 1, Chromogranin A precursor, ChromograninA, CMGA, ER-37, Pancreastatin, Parastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Secretory protein I, SP I, SP-I, SP1, SPI, Vasostatin, Vasostatin I, Vasostatin II

Active Protein: Active protein

Activity: A DNA sequence encoding theMouse Chromogranin-A/Chga(P26339) (457Ile-717Leu) was expressed with a polyhistidine tag at the N-terminus.

Protein Construction: A DNA sequence encoding theMouse Chromogranin-A/Chga(P26339) (457Ile-717Leu) was expressed with a polyhistidine tag at the N-terminus.

Fusion Tag: N/C-His

Species: Mouse

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 31kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.Catestatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines.Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation . Pyroglutaminated (pGlu)-serpinin exerts an antiapoptotic effect on cells exposed to oxidative stress .

Research Area: N/A