Recombinant Mouse CD27/TNFRSF7 Protein (Fc & His Tag) | PKSM041253

Recombinant Mouse CD27/TNFRSF7 Protein (Fc & His Tag) | PKSM041253 | Gentaur US, UK & Europe Disrtribition

Synonyms: CD27 antigen; CD27L receptor; T-cell activation antigen CD27; Tumor necrosis factor receptor superfamily member 7;S152;Tnfrsf7;Tp55

Active Protein: N/A

Activity: Recombinant Mouse CD27 antigen is produced by our Mammalian expression system and the target gene encoding Pro24-Arg182 is expressed with a Fc, 6His tag at the C-terminus.

Protein Construction: Recombinant Mouse CD27 antigen is produced by our Mammalian expression system and the target gene encoding Pro24-Arg182 is expressed with a Fc, 6His tag at the C-terminus.

Fusion Tag: C-Fc-6His

Species: Mouse

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 45.8 kDa

Formulation: Lyophilized from a 0.2μm filtered solution of PBS, pH7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Research Area: N/A