Recombinant Lactate Dehydrogenase A Monoclonal Antibody | E-AB-81451

Recombinant Lactate Dehydrogenase A Monoclonal Antibody | E-AB-81451 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Application: WB

Research Area: Cancer, Metabolism, Signal Transduction

Background: LDHA, also named as LDH-M and NY-REN-59, is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours, and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

Lead Time: 7~10 days

Concentration: 300 μg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: N/A

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification: Affinity Purified

Dilution: WB 1:1000-1:2000

Conjugation: Unconjugated

Calculated Molecular Weight: 37kDa

Observed Molecular Weight: 37kDa

Clonality: Rabbit Monoclonal