Recombinant Human SEMA4B Protein (His Tag) | PKSH033020

Recombinant Human SEMA4B Protein (His Tag) | PKSH033020 | Gentaur US, UK & Europe Disrtribition

Synonyms: Semaphorin-4B; KIAA1745; SEMAC and SEMA4B

Active Protein: N/A

Activity: Recombinant Human Semaphorin 4B is produced by our Mammalian expression system and the target gene encoding Leu39-Glu712 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Semaphorin 4B is produced by our Mammalian expression system and the target gene encoding Leu39-Glu712 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 75.7 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.

Reconstitution: Not Applicable

Background: The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain; one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.

Research Area: Neuroscience