Recombinant Human PGA4/Pepsinogen A Protein (His Tag)(Active) | PKSH030741

Recombinant Human PGA4/Pepsinogen A Protein (His Tag)(Active) | PKSH030741 | Gentaur US, UK & Europe Disrtribition

Synonyms: FLJ58952;FLJ77962;PGA3;PGA4;PGA5

Active Protein: Active protein

Activity: A DNA sequence encoding the human PGA4 (NP_001073276.1) (Met 1-Ala 388) was fused with a polyhistidine tag at the C-terminus.

Protein Construction: A DNA sequence encoding the human PGA4 (NP_001073276.1) (Met 1-Ala 388) was fused with a polyhistidine tag at the C-terminus.

Fusion Tag: C-His

Species: Human

Expressed Host: HEK293 Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 97 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 41.7 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: PGA4 (Pepsinogen 4; group I); or Pepsinogen A; is a member of the peptidase A1 family. Pepsin is expressed as a pro-form zymogen; pepsinogen; whose primary structure has an additional 44 amino acids. Pepsin is stored as pepsinogen so it will only be released when needed; and does not digest the body's own proteins in the stomach's lining. Five types of zymogens of pepsins; gastric digestive proteinases; are known: pepsinogens A; B; and F; progastricsin; and prochymosin. There are two major groups of pepsinogen; namely pepsinogen A (PGA) and pepsinogen C (PGC) (or progastricsin); and each frequently has isozymogens. The PGA3; PGA4 and PGA5 genes encode identical human pepsinogen A enzymes.

Research Area: N/A