Recombinant Human Interleukin-2/IL-2 Protein (Mutant)(Active) | PKSH033625

Recombinant Human Interleukin-2/IL-2 Protein (Mutant)(Active) | PKSH033625 | Gentaur US, UK & Europe Disrtribition

Synonyms: Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL3

Active Protein: Active protein

Activity: Recombinant Human Interleukin-2 is produced by our Mammalian expression system and the target gene encoding Ala21-Thr153(L100F;R101D;L105V;I106V;I112F) is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Interleukin-2 is produced by our Mammalian expression system and the target gene encoding Ala21-Thr153(L100F;R101D;L105V;I106V;I112F) is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 16.5 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cells.

Research Area: immunology