Recombinant Human IL-1A/IL-1α Protein | PKSH033458

Recombinant Human IL-1A/IL-1α Protein | PKSH033458 | Gentaur US, UK & Europe Disrtribition

Synonyms: Interleukin-1 Alpha, IL-1 Alpha, Hematopoietin-1, IL1A, IL1F1

Active Protein: Active protein

Activity: Recombinant Human IL-1A is produced by our E.coli expression system and the target gene encoding Ser113-Ala271 is expressed.

Protein Construction: Recombinant Human IL-1A is produced by our E.coli expression system and the target gene encoding Ser113-Ala271 is expressed.

Fusion Tag: N/A

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 18 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.

Research Area: immunology, metabolism