Recombinant Human GH1/Growth hormone 1 Protein (Active) | PKSH030498

Recombinant Human GH1/Growth hormone 1 Protein (Active) | PKSH030498 | Gentaur US, UK & Europe Disrtribition

Synonyms: GH;GH-N;GH1;GHB5;GHN;Growth hormone 1;hGH-N;IGHD1B

Active Protein: Active protein

Activity: A DNA sequence encoding the human GH1 (P01241) (Phe27-Phe217) was expressed.

Protein Construction: A DNA sequence encoding the human GH1 (P01241) (Phe27-Phe217) was expressed.

Fusion Tag:

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 22.1 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene; along with four other related genes; is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones; leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

Research Area: Signal Transduction, Developmental Biology,