Description
Recombinant Human Follistatin 288/FST Protein | PKSH033674 | Gentaur US, UK & Europe Disrtribition
Synonyms: follistatin isoform FST317; Follistatin; FS; FSActivin-binding protein; FST
Active Protein: N/A
Activity: Recombinant Human Follistatin is produced by our Mammalian expression system and the target gene encoding Gly30-Asn317 is expressed.
Protein Construction: Recombinant Human Follistatin is produced by our Mammalian expression system and the target gene encoding Gly30-Asn317 is expressed.
Fusion Tag: N/A
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 32.4 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Follistatin 288 is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid. Human follistatin 288 cDNA encodes a 317 amino acid (aa) protein with a 29aa signal sequence, and a 288 aa mature region.Follistatin shows the highest affinity for activins due to its extended configuration. Genetic deletion of follistatin in mice, or expression of only the Follistatin form, is perinatally lethal due to defects of lung, skin and musculoskeletal system. Follistatins also regulate hematopoietic stem cell adhesion to fibronectin via FS2.
Research Area: Signal Transduction, epigenetics and nuclear signal,
