Recombinant Human CD8 Beta Chain/CD8B (C-Fc) | PKSH033943

Recombinant Human CD8 Beta Chain/CD8B (C-Fc) | PKSH033943 | Gentaur US, UK & Europe Disrtribition

Synonyms: T-Cell Surface Glycoprotein CD8 Beta Chain; CD8b; CD8B; CD8B1

Active Protein: N/A

Activity: Recombinant Human T-Cell Surface Glycoprotein CD8 beta Chain is produced by our Mammalian expression system and the target gene encoding Leu22-Pro170 is expressed with a Fc tag at the C-terminus.

Protein Construction: Recombinant Human T-Cell Surface Glycoprotein CD8 beta Chain is produced by our Mammalian expression system and the target gene encoding Leu22-Pro170 is expressed with a Fc tag at the C-terminus.

Fusion Tag: C-Fc

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 43.7 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Research Area: immunology