Description
Recombinant Human Carboxypeptidase B1/CPB1 Protein (His Tag) | PKSH032171 | Gentaur US, UK & Europe Disrtribition
Synonyms: Carboxypeptidase B; Pancreas-Specific Protein; PASP; CPB1; CPB; PCPB
Active Protein: N/A
Activity: Recombinant Human Carboxypeptidase B is produced by our Mammalian expression system and the target gene encoding His16-Tyr417 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Carboxypeptidase B is produced by our Mammalian expression system and the target gene encoding His16-Tyr417 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 46.9 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
Reconstitution: Not Applicable
Background: Carboxypeptidase B1 is an exopeptidase which specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. Expressed mainly in pancreas, CPB1 is a useful serum marker for acute pancreatitis and pancreatic graft rejection.Human CPB1 consists of a signal peptide, a pro region, and a mature chain. The purified rhCPB1 corresponds to the pro form, which can be activated by trypsin, the only pancreatic protease capable of generating active enzyme from the zymogen in vitro.
Research Area: Signal Transduction, metabolism,
