Recombinant Human Butyrophilin Subfamily 1 Member A1/BTN1A1 (C-6His-Avi) Biotinylated | PKSH033984

Recombinant Human Butyrophilin Subfamily 1 Member A1/BTN1A1 (C-6His-Avi) Biotinylated | PKSH033984 | Gentaur US, UK & Europe Disrtribition

Synonyms: Butyrophilin Subfamily 1 Member A1; BT; BTN1A1; BTN

Active Protein: N/A

Activity: Biotinylated Recombinant Human Butyrophilin Subfamily 1 Member A1 is produced by our Mammalian expression system and the target gene encoding Ala27-Arg242 is expressed with a 6His, Avi tag at the C-terminus.

Protein Construction: Biotinylated Recombinant Human Butyrophilin Subfamily 1 Member A1 is produced by our Mammalian expression system and the target gene encoding Ala27-Arg242 is expressed with a 6His, Avi tag at the C-terminus.

Fusion Tag: C-6His-Avi

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 26.8 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

Research Area: Cardiovascular