Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His) | PKSQ050102

Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His) | PKSQ050102 | Gentaur US, UK & Europe Disrtribition

Synonyms: Thymic stromal lymphopoietin; Thymic stroma-derived lymphopoietin; TSLP 

Active Protein: Active protein

Activity: Recombinant Cynomolgus Thymic Stromal Lymphopoietin is produced by our E.coli expression system and the target gene encoding Tyr29-Gln159(Glu37Gln) is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Cynomolgus Thymic Stromal Lymphopoietin is produced by our E.coli expression system and the target gene encoding Tyr29-Gln159(Glu37Gln) is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Cynomolgus

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 16.2 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.

Research Area: N/A